Rapid colorimetric assay for acetaminophen without salicylate or phenylephrine interference.
نویسندگان
چکیده
A simple rapid, and economical procedure is presented for the quantitative determination of acetaminophen in serum. Acetaminophen is extracted into solvent, and, when back-extracted into base, is simultaneously reacted with Folin-Ciocalteau reagent to form a colored complex. The potential interference of bilirubin is eliminated by treatment with p-diazobenzene sulfonic acid. Results obtained with this method agree with those obtained by "high-pressure" liquid chromatography.
منابع مشابه
A rapid, simple acetaminophen determination is available.
contribution in the measurement. Concentration of active chemical ingredients , additives, timing parameters, and electronic time constants are variables that help to establish the positive characteristics and define the limitations of each method. To the Editor: We read with interest the recent Letter of Rosenbaum et al. (1) expressing their concerns about possible interference by salicylates ...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 28 5 شماره
صفحات -
تاریخ انتشار 1982